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Limited demethylation leaves mosaic-type methylation states in cloned bovine pre-implantation embryos
Cloning by nuclear transfer (NT) has been riddled with difficulties: most clones die before birth and survivors frequently display growth abnormalities. The cross-species similarity in abnormalities observed in cloned fetuses/animals leads us to suspect the fidelity of epigenetic reprogramming of th...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC125883/ https://ncbi.nlm.nih.gov/pubmed/11867537 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/21.5.1092 |
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