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Regulation of receptor protein-tyrosine phosphatase α by oxidative stress

The presence of two protein-tyrosine phosphatase (PTP) domains is a striking feature in most transmembrane receptor PTPs (RPTPs). The function of the generally inactive membrane-distal PTP domain (RPTP-D2) is unknown. Here we report that an intramolecular interaction between the spacer region (Sp) a...

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Autores principales: Blanchetot, Christophe, Tertoolen, Leon G.J., den Hertog, Jeroen
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2002
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC125870/
https://ncbi.nlm.nih.gov/pubmed/11847098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/21.4.493
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