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The structure of bovine IF(1), the regulatory subunit of mitochondrial F-ATPase

In mitochondria, the hydrolytic activity of ATP synthase is regulated by an inhibitor protein, IF(1). Its binding to ATP synthase depends on pH, and below neutrality, IF(1) is dimeric and forms a stable complex with the enzyme. At higher pH values, IF(1) forms tetramers and is inactive. In the 2.2 Å...

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Detalhes bibliográficos
Main Authors: Cabezón, E., Runswick, M.J., Leslie, A.G.W., Walker, J.E.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC125800/
https://ncbi.nlm.nih.gov/pubmed/11742976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.24.6990
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