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The structure of bovine IF(1), the regulatory subunit of mitochondrial F-ATPase

In mitochondria, the hydrolytic activity of ATP synthase is regulated by an inhibitor protein, IF(1). Its binding to ATP synthase depends on pH, and below neutrality, IF(1) is dimeric and forms a stable complex with the enzyme. At higher pH values, IF(1) forms tetramers and is inactive. In the 2.2 Å...

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Autori principali: Cabezón, E., Runswick, M.J., Leslie, A.G.W., Walker, J.E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC125800/
https://ncbi.nlm.nih.gov/pubmed/11742976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.24.6990
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