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A simple mechanism for co-dependence on two activators at an Escherichia coli promoter

The Escherichia coli melAB promoter is co-dependent upon two transcription activators, MelR and the cyclic AMP receptor protein, CRP. In this study we demonstrate positive co-operativity between the binding of MelR and CRP at the melAB promoter, which provides a simple mechanism for its co-dependenc...

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Detalhes bibliográficos
Main Authors: Wade, Joseph T., Belyaeva, Tamara A., Hyde, Eva I., Busby, Stephen J.W.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC125794/
https://ncbi.nlm.nih.gov/pubmed/11742992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.24.7160
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