RTG-dependent mitochondria to nucleus signaling is negatively regulated by the seven WD-repeat protein Lst8p

In cells with reduced mitochondrial function, RTG1, 2 and 3 are required for expression of genes involved in glutamate synthesis. Glutamate negatively regulates RTG-dependent gene expression upstream of Rtg2p, which, in turn, acts upstream of the bHLH/Zip transcription factors, Rtg1p and Rtg3p. Here...

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Опубликовано в::	EMBO J
Главные авторы:	Liu, Zhengchang, Sekito, Takayuki, Epstein, Charles B., Butow, Ronald A.
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Nature Publishing Group 2001
Предметы:	Article
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125777/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11742997/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.24.7209
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