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Dynamic effects of antibody-dependent enhancement on the fitness of viruses

Antibody-dependent enhancement (ADE), a phenomenon in which viral replication is increased rather than decreased by immune sera, has been observed in vitro for a large number of viruses of public health importance, including flaviviruses, coronaviruses, and retroviruses. The most striking in vivo ex...

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Bibliographic Details
Main Authors: Cummings, Derek A. T., Schwartz, Ira B., Billings, Lora, Shaw, Leah B., Burke, Donald S.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2005
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1257724/
https://ncbi.nlm.nih.gov/pubmed/16217017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0507320102
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