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Hemin-activated macrophages home to the pancreas and protect from acute pancreatitis via heme oxygenase-1 induction

Hemin upregulates heme oxygenase-1 (HO-1), a stress-induced enzyme implicated in protection from a variety of injuries while its related isoform HO-2 is constitutively expressed. The role of hemin or HO-1 in the pancreas and their potential modulation of pancreatic injury are unknown. We show that H...

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書誌詳細
主要な著者: Nakamichi, Ikuo, Habtezion, Aida, Zhong, Bihui, Contag, Christopher H., Butcher, Eugene C., Omary, M. Bishr
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 2005
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1257535/
https://ncbi.nlm.nih.gov/pubmed/16239966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI24912
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