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Hemin-activated macrophages home to the pancreas and protect from acute pancreatitis via heme oxygenase-1 induction
Hemin upregulates heme oxygenase-1 (HO-1), a stress-induced enzyme implicated in protection from a variety of injuries while its related isoform HO-2 is constitutively expressed. The role of hemin or HO-1 in the pancreas and their potential modulation of pancreatic injury are unknown. We show that H...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Clinical Investigation
2005
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1257535/ https://ncbi.nlm.nih.gov/pubmed/16239966 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI24912 |
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