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Rheumatoid arthritis as a hyper-endoplasmic reticulum-associated degradation disease
We introduce Synoviolin as a novel pathogenic factor in rheumatoid arthritis (RA). Experimental studies indicate that this endoplasmic reticulum (ER)-resident E3 ubiquitin ligase has important functions in the ER-associated degradation (ERAD) system, an essential system for ER homeostasis. Overexpre...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1257448/ https://ncbi.nlm.nih.gov/pubmed/16207344 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar1808 |
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