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Topoisomerase II can unlink replicating DNA by precatenane removal

We have analysed the role of topoisomerase II (topo II) in plasmid DNA replication in Xenopus egg extracts, using specific inhibitors and two-dimensional gel electrophoresis of replication products. Topo II is dispensable for nuclear assembly and complete replication of plasmid DNA but is required f...

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Autors principals: Lucas, Isabelle, Germe, Thomas, Chevrier-Miller, Marianne, Hyrien, Olivier
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC125741/
https://ncbi.nlm.nih.gov/pubmed/11707421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.22.6509
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