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Crystal structure of the ankyrin repeat domain of Bcl-3: a unique member of the IκB protein family

IκB proteins associate with the transcription factor NF-κB via their ankyrin repeat domain. Bcl-3 is an unusual IκB protein because it is primarily nucleoplasmic and can lead to enhanced NF-κB-dependent transcription, unlike the prototypical IκB protein IκBα, which inhibits NF-κB activity by retaini...

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Bibliografske podrobnosti
Main Authors: Michel, Fabrice, Soler-Lopez, Montserrat, Petosa, Carlo, Cramer, Patrick, Siebenlist, Ulrich, Müller, Christoph W.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2001
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC125740/
https://ncbi.nlm.nih.gov/pubmed/11707390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.22.6180
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