Gfi1 functions downstream of Math1 to control intestinal secretory cell subtype allocation and differentiation

Gfi1 is a transcriptional repressor implicated in lymphomagenesis, neutropenia, and hematopoietic development, as well as ear and lung development. Here, we demonstrate that Gfi1 functions downstream of Math1 in intestinal secretory lineage differentiation. Gfi1(-/-) mice lack Paneth cells, have few...

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Bibliographic Details
Main Authors: Shroyer, Noah F., Wallis, Deeann, Venken, Koen J.T., Bellen, Hugo J., Zoghbi, Huda Y.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2005
Subjects:
Research Communications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1257395/
https://ncbi.nlm.nih.gov/pubmed/16230531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1353905
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