ShcA and Grb2 mediate polyoma middle T antigen-induced endothelial transformation and Gab1 tyrosine phosphorylation

Middle T antigen (PymT) is the principal transforming component of polyomavirus, and rapidly induces hemangiomas in neonatal mice. PymT, a membrane-associated scaffold, recruits and activates Src family tyrosine kinases, and, once tyrosine phosphorylated, binds proteins with PTB and SH2 domains such...

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Detalhes bibliográficos

Publicado no:	EMBO J
Principais autores:	Ong, Siew Hwa, Dilworth, Stephen, Hauck-Schmalenberger, Ingrid, Pawson, Tony, Kiefer, Friedemann
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 2001
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125714/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11707404/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.22.6327
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