X-ray structure of the orphan nuclear receptor RORβ ligand-binding domain in the active conformation

The retinoic acid-related orphan receptor β (RORβ) exhibits a highly restricted neuronal-specific expression pattern in brain, retina and pineal gland. So far, neither a natural RORβ target gene nor a functional ligand have been identified, and the physiological role of the receptor is not well unde...

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Publié dans:	EMBO J
Auteurs principaux:	Stehlin, Catherine, Wurtz, Jean-Marie, Steinmetz, Anke, Greiner, Erich, Schüle, Roland, Moras, Dino, Renaud, Jean-Paul
Format:	Artigo
Langue:	Inglês
Publié:	Nature Publishing Group 2001
Sujets:	Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125710/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11689423/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.21.5822
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