Antagonistic effects of T-Ag and VP16 reveal a role for RNA pol II elongation on alternative splicing

Here we investigate the promoter control of alternative splicing by studying two transcriptional activators on templates under replicating conditions. SV40 large T-antigen (T-Ag) activates template replication only 2-fold but transcription 25-fold. T-Ag-mediated replication, reported to inhibit RNA...

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Hauptverfasser: Kadener, Sebastián, Cramer, Paula, Nogués, Guadalupe, Cazalla, Demián, de la Mata, Manuel, Fededa, Juan Pablo, Werbajh, Santiago E., Srebrow, Anabella, Kornblihtt, Alberto R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2001
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC125675/
https://ncbi.nlm.nih.gov/pubmed/11598018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.20.5759
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