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Link of the unique oncogenic properties of adenovirus type 9 E4-ORF1 to a select interaction with the candidate tumor suppressor protein ZO-2

Adenovirus type 9 (Ad9) is distinct among human adenoviruses because it elicits solely mammary tumors in animals and its primary oncogenic determinant is the E4 region-encoded ORF1 (E4-ORF1) protein. We report here that the PDZ domain-containing protein ZO-2, which is a candidate tumor suppressor pr...

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Detalhes bibliográficos
Main Authors: Glaunsinger, Britt A., Weiss, Robert S., Lee, Siu Sylvia, Javier, Ronald
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC125668/
https://ncbi.nlm.nih.gov/pubmed/11598001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.20.5578
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