Nalaganje...
Structure and function of the N-terminal 40 kDa fragment of human PMS2: a monomeric GHL ATPase
Human MutLα, a heterodimer of hMLH1 and hPMS2, is essential for DNA mismatch repair. Inactivation of the hmlh1 or hpms2 genes by mutation or epigenesis causes genomic instability and a predisposition to hereditary non-polyposis cancer. We report here the X-ray crystal structures of the conserved N-t...
Shranjeno v:
| Main Authors: | , , |
|---|---|
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2001
|
| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC125661/ https://ncbi.nlm.nih.gov/pubmed/11574484 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.19.5521 |
| Oznake: |
Označite
Brez oznak, prvi označite!
|