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Crystal structure of human protein kinase CK2: insights into basic properties of the CK2 holoenzyme

The crystal structure of a fully active form of human protein kinase CK2 (casein kinase 2) consisting of two C-terminally truncated catalytic and two regulatory subunits has been determined at 3.1 Å resolution (Protein Data Bank code: 1JWH). In the CK2 complex the regulatory subunits form a stable d...

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Bibliografiske detaljer
Udgivet i:EMBO J
Principais autores: Niefind, Karsten, Guerra, Barbara, Ermakowa, Inessa, Issinger, Olaf-Georg
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2001
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125641/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11574463/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.19.5320
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