Sir2p exists in two nucleosome-binding complexes with distinct deacetylase activities
The absolute requirement for the histone deacetylase activity of Sir2p in silencing coupled with the conservation of Sir2p-like proteins in larger eukaryotes suggests that this molecule plays an important role in gene regulation in all organisms. Here we report the purification and characterization...
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| Publicado no: | EMBO J |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125569/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11500379/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.16.4522 |
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