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Regulation of elongation factor 2 kinase by p90(RSK1) and p70 S6 kinase

Elongation factor 2 kinase (eEF2k) phosphorylates and inactivates eEF2. Insulin induces dephosphorylation of eEF2 and inactivation of eEF2 kinase, and these effects are blocked by rapamycin, which inhibits the mammalian target of rapamycin, mTOR. However, the signalling mechanisms underlying these e...

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Bibliografiske detaljer
Udgivet i:EMBO J
Principais autores: Wang, Xuemin, Li, Wei, Williams, Michayla, Terada, Naohiro, Alessi, Dario R., Proud, Christopher G.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2001
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125559/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11500364/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.16.4370
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