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The interaction of insulin-like growth factor-I with the N-terminal domain of IGFBP-5

Insulin-like growth factors (IGFs) are key regulators of cell proliferation, differentiation and transformation, and are thus pivotal in cancer, especially breast, prostate and colon neoplasms. They are also important in many neurological and bone disorders. Their potent mitogenic and anti-apoptotic...

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Détails bibliographiques
Publié dans:EMBO J
Auteurs principaux: Żesławski, Wojciech, Beisel, Hans-Georg, Kamionka, Mariusz, Kalus, Wenzel, Engh, Richard A., Huber, Robert, Lang, Kurt, Holak, Tad A.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2001
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125553/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11447105/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.14.3638
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