Disruption of mannose activation in Leishmania mexicana: GDP-mannose pyrophosphorylase is required for virulence, but not for viability
In eukaryotes, the enzyme GDP-mannose pyrophosphorylase (GDPMP) is essential for the formation of GDP-mannose, the central activated mannose donor in glycosylation reactions. Deletion of its gene is lethal in fungi, most likely as a consequence of disrupted glycoconjugate biosynthesis. Furthermore,...
Na minha lista:
| Publicado no: | EMBO J |
|---|---|
| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2001
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125538/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11447107/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.14.3657 |
| Tags: |
Sem tags, seja o primeiro a adicionar uma tag!
|