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PTP-PEST, a scaffold protein tyrosine phosphatase, negatively regulates lymphocyte activation by targeting a unique set of substrates

There is increasing interest in elucidating the mechanisms involved in the negative regulation of lymphocyte activation. Herein, we show that the cytosolic protein tyrosine phosphatase PTP-PEST is expressed abundantly in a wide variety of haemopoietic cell types, including B cells and T cells. In a...

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Detalhes bibliográficos
Main Authors: Davidson, Dominique, Veillette, André
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC125513/
https://ncbi.nlm.nih.gov/pubmed/11432829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.13.3414
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