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The adaptor molecule Disabled-2 links the transforming growth factor β receptors to the Smad pathway
Using a genetic complementation approach we have identified disabled-2 (Dab2), a structural homolog of the Dab1 adaptor molecule, as a critical link between the transforming growth factor β (TGFβ) receptors and the Smad family of proteins. Expression of wild-type Dab2 in a TGFβ-signaling mutant rest...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2001
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC125498/ https://ncbi.nlm.nih.gov/pubmed/11387212 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.11.2789 |
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