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Activated MEK5 induces serial assembly of sarcomeres and eccentric cardiac hypertrophy
Mitogen-activated protein kinase (MAPK) pathways couple intrinsic and extrinsic signals to hypertrophic growth of cardiomyocytes. The MAPK kinase MEK5 activates the MAPK ERK5. To investigate the potential involvement of MEK5–ERK5 in cardiac hypertrophy, we expressed constitutively active and dominan...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC125475/ https://ncbi.nlm.nih.gov/pubmed/11387209 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.11.2757 |
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