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The sortilin cytoplasmic tail conveys Golgi–endosome transport and binds the VHS domain of the GGA2 sorting protein

Sortilin belongs to a growing family of multiligand type-1 receptors with homology to the yeast receptor Vps10p. Based on structural features and sortilin’s intracellular predominance, we have proposed it to be a sorting receptor for ligands in the synthetic pathway as well as on the cell membrane....

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Publicat a:EMBO J
Autors principals: Nielsen, Morten S., Madsen, Peder, Christensen, Erik I., Nykjær, Anders, Gliemann, Jørgen, Kasper, Dagmar, Pohlmann, Regina, Petersen, Claus M.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2001
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125444/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11331584/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.9.2180
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