Structure and functional interactions of the Tsg101 UEV domain

Human Tsg101 plays key roles in HIV budding and in cellular vacuolar protein sorting (VPS). In performing these functions, Tsg101 binds both ubiquitin (Ub) and the PTAP tetrapeptide ‘late domain’ motif located within the viral Gag protein. These interactions are mediated by the N-terminal domain of...

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Publié dans:	EMBO J
Auteurs principaux:	Pornillos, Owen, Alam, Steven L., Rich, Rebecca L., Myszka, David G., Davis, Darrell R., Sundquist, Wesley I.
Format:	Artigo
Langue:	Inglês
Publié:	Nature Publishing Group 2002
Sujets:	Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125378/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12006492/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/21.10.2397
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