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Membrane transport in Caenorhabditis elegans: an essential role for VPS34 at the nuclear membrane

Here we present a detailed genetic analysis of let-512/vps34 that encodes the Caenorhabditis elegans homologue of the yeast phosphatidylinositol 3-kinase Vps34p. LET-512/VPS34 has essential functions and is ubiquitously expressed in all tissues and developmental stages. It accumulates at a perinucle...

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Detalhes bibliográficos
Main Authors: Roggo, Lorenz, Bernard, Vincent, Kovacs, Attila L., Rose, Ann M., Savoy, Fabienne, Zetka, Monique, Wymann, Matthias P., Müller, Fritz
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC125367/
https://ncbi.nlm.nih.gov/pubmed/11927551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/21.7.1673
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