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Impaired postnatal hepatocyte proliferation and liver regeneration in mice lacking c-jun in the liver
Mice lacking the AP-1 transcription factor c-jun die at mid-gestation showing heart defects and impaired hepatogenesis. To inactivate c-jun in hepatocytes, mice carrying a floxed c-jun allele were generated. Perinatal liver-specific c-jun deletion caused reduced hepatocyte proliferation and decrease...
Tallennettuna:
| Päätekijät: | , , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Oxford University Press
2002
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC125360/ https://ncbi.nlm.nih.gov/pubmed/11927562 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/21.7.1782 |
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