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Ras activation of a Rac1 exchange factor, Tiam1, mediates neurotrophin-3-induced Schwann cell migration

Endogenous neurotrophins positively and negatively regulate migration of premyelinating Schwann cells before the initiation of myelination. Neurotrophin-3 (NT3) acting through the TrkC receptor tyrosine kinase stimulates Schwann cell migration via the Rho GTPases Rac1 and Cdc42. We previously demons...

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Bibliografische gegevens
Hoofdauteurs: Yamauchi, Junji, Miyamoto, Yuki, Tanoue, Akito, Shooter, Eric M., Chan, Jonah R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2005
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1253593/
https://ncbi.nlm.nih.gov/pubmed/16203995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0507125102
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