Modification of the human thymine-DNA glycosylase by ubiquitin-like proteins facilitates enzymatic turnover

DNA glycosylases initiate base excision repair (BER) through the generation of potentially harmful abasic sites (AP sites) in DNA. Human thymine-DNA glycosylase (TDG) is a mismatch-specific uracil/thymine-DNA glycosylase with an implicated function in the restoration of G·C base pairs at sites of cy...

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Detalhes bibliográficos

Publicado no:	EMBO J
Principais autores:	Hardeland, Ulrike, Steinacher, Roland, Jiricny, Josef, Schär, Primo
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 2002
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125358/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11889051/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/21.6.1456
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