Importins fulfil a dual function as nuclear import receptors and cytoplasmic chaperones for exposed basic domains

Many nuclear transport pathways are mediated by importin β-related transport receptors. Here, we identify human importin (Imp) 4b as well as mouse Imp4a, Imp9a and Imp9b as novel family members. Imp4a mediates import of the ribosomal protein (rp) S3a, while Imp9a and Imp9b import rpS7, rpL18a and ap...

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Pubblicato in:	EMBO J
Autori principali:	Jäkel, Stefan, Mingot, José-Manuel, Schwarzmaier, Petra, Hartmann, Enno, Görlich, Dirk
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Publishing Group 2002
Soggetti:	Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125346/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11823430/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/21.3.377
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