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Solution structure of conserved AGNN tetraloops: insights into Rnt1p RNA processing

Rnt1p, the yeast orthologue of RNase III, cleaves rRNAs, snRNAs and snoRNAs at a stem capped with conserved AGNN tetraloop. Here we show that 9 bp long stems ending with AGAA or AGUC tetraloops bind to Rnt1p and direct specific but sequence-independent RNA cleavage when provided with stems longer th...

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Udgivet i:EMBO J
Principais autores: Lebars, Isabelle, Lamontagne, Bruno, Yoshizawa, Satoko, Abou Elela, Sherif, Fourmy, Dominique
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2001
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Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125334/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11743001/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.24.7250
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