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The chromatin remodelling factor Brg-1 interacts with β-catenin to promote target gene activation
Wnt-induced formation of nuclear Tcf–β-catenin complexes promotes transcriptional activation of target genes involved in cell fate decisions. Inappropriate expression of Tcf target genes resulting from mutational activation of this pathway is also implicated in tumorigenesis. The C-terminus of β-cat...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC125268/ https://ncbi.nlm.nih.gov/pubmed/11532957 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.17.4935 |
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