The 65 and 110 kDa SR-related proteins of the U4/U6⋅U5 tri-snRNP are essential for the assembly of mature spliceosomes

The association of the U4/U6⋅U5 tri-snRNP with pre-spliceosomes is a poorly understood step in the spliceosome assembly pathway. We have identified two human tri-snRNP proteins (of 65 and 110 kDa) that play an essential role in this process. Characterization by cDNA cloning of the 65 and 110 kDa pro...

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Pubblicato in:	EMBO J
Autori principali:	Makarova, Olga V., Makarov, Evgeny M., Lührmann, Reinhard
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Publishing Group 2001
Soggetti:	Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125249/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11350945/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.10.2553
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