The 65 and 110 kDa SR-related proteins of the U4/U6⋅U5 tri-snRNP are essential for the assembly of mature spliceosomes

The association of the U4/U6⋅U5 tri-snRNP with pre-spliceosomes is a poorly understood step in the spliceosome assembly pathway. We have identified two human tri-snRNP proteins (of 65 and 110 kDa) that play an essential role in this process. Characterization by cDNA cloning of the 65 and 110 kDa pro...

Ausführliche Beschreibung

Bibliografische Detailangaben

Veröffentlicht in:	EMBO J
Hauptverfasser:	Makarova, Olga V., Makarov, Evgeny M., Lührmann, Reinhard
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Publishing Group 2001
Schlagworte:	Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125249/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11350945/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.10.2553
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!