Cerebral energetics and spiking frequency: The neurophysiological basis of fMRI

Functional MRI (fMRI) is widely assumed to measure neuronal activity, but no satisfactory mechanism for this linkage has been identified. Here we derived the changes in the energetic component from the blood oxygenation level-dependent (BOLD) fMRI signal and related it to changes in the neuronal spi...

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Bibliographic Details

Published in:	Proc Natl Acad Sci U S A
Main Authors:	Smith, Arien J., Blumenfeld, Hal, Behar, Kevin L., Rothman, Douglas L., Shulman, Robert G., Hyder, Fahmeed
Format:	Artigo
Language:	Inglês
Published:	National Academy of Sciences 2002
Subjects:	Biological Sciences
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125038/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12134056/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.132272199
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