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High doses of methylprednisolone are required for the treatment of collagenase-induced intracerebral hemorrhage in rats

Methylprednisolone (MP) was evaluated for the treatment of intracerebral hemorrhage in a Sprague-Dawley rat model of cerebral hematoma induced by subcortical injection of collagenase. At 1 and 24 h after the injection, MP was administered intraperitoneally (IP) at a concentration of 10, 35, or 100 m...

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Detalhes bibliográficos
Main Authors: Lema, Pablo Patricio, Girard, Christiane, Vachon, Pascal
Formato: Artigo
Idioma:Inglês
Publicado em: Canadian Veterinary Medical Association 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1250236/
https://ncbi.nlm.nih.gov/pubmed/16479722
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