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The CcmE protein of the c-type cytochrome biogenesis system: Unusual in vitro heme incorporation into apo-CcmE and transfer from holo-CcmE to apocytochrome

Three key steps of cytochrome c biogenesis in many Gram-negative bacteria, the uptake of heme by the heme chaperone CcmE, the covalent attachment of heme to CcmE, and its subsequent release from CcmE to an apocytochrome c, have been achieved in vitro. apo-CcmE from Escherichia coli preferentially bo...

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Autors principals: Daltrop, Oliver, Stevens, Julie M., Higham, Christopher W., Ferguson, Stuart J.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC124985/
https://ncbi.nlm.nih.gov/pubmed/12119398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.152120699
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