The essential role of Cited2, a negative regulator for HIF-1α, in heart development and neurulation

Cited2 is a cAMP-responsive element-binding protein (CBP)/p300 interacting transcriptional modulator and a proposed negative regulator for hypoxia-inducible factor (HIF)-1α through its competitive binding with HIF-1α to CBP/p300. Disruption of the gene encoding Cited2 is embryonic lethal because of...

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Bibliographic Details
Main Authors: Yin, Zhan, Haynie, Jennifer, Yang, Xiaoming, Han, Baoguang, Kiatchoosakun, Songsak, Restivo, Joseph, Yuan, Saying, Prabhakar, Nanduri R., Herrup, Karl, Conlon, Ronald A., Hoit, Brian D., Watanabe, Michiko, Yang, Yu-Chung
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2002
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC124951/
https://ncbi.nlm.nih.gov/pubmed/12149478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.162371799
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