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Targeting Phospholamban by Gene Transfer in Human Heart Failure

BACKGROUND: Myocardial cells from failing human hearts are characterized by abnormal calcium handling, a negative force-frequency relationship, and decreased sarcoplasmic reticulum Ca(2+) ATPase (SERCA2a) activity. In this study, we tested whether contractile function can be improved by decreasing t...

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Bibliografische gegevens
Hoofdauteurs: del Monte, Federica, Harding, Sian E., William Dec, G., Gwathmey, Judith K., Hajjar, Roger J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2002
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1249505/
https://ncbi.nlm.nih.gov/pubmed/11864915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/hc0802.105564
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