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Induction Speed Is Not a Determinant of Propofol Pharmacodynamics

SUMMARY: We used individual pharmacodynamic modeling to demonstrate that different sedation endpoints occur at the same effect site propofol concentration, independent of the infusion rate of propofol. BACKGROUND: Evidence suggests that the rate at which they are infused may influence plasma-effect...

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Detalhes bibliográficos
Main Authors: Doufas, Anthony G., Bakhshandeh, Maryam, Bjorksten, Andrew R., Shafer, Steven L., Sessler, Daniel I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1249471/
https://ncbi.nlm.nih.gov/pubmed/15505446
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