Mechanisms of polarization of the shape of fibroblasts and epitheliocytes: Separation of the roles of microtubules and Rho-dependent actin–myosin contractility

Cultured fibroblasts possess a characteristic polarized phenotype manifested by an elongate cell body with an anterior lamella whose cell edge is divided into protrusion-forming and inactive zones. Disruption of the fibroblast microtubule cytoskeleton leads to an increase in Rho-dependent acto-myosi...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Omelchenko, T., Vasiliev, J. M., Gelfand, I. M., Feder, H. H., Bonder, E. M.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 2002
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC124937/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12149446/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.152339899
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