Mechanisms of polarization of the shape of fibroblasts and epitheliocytes: Separation of the roles of microtubules and Rho-dependent actin–myosin contractility

Cultured fibroblasts possess a characteristic polarized phenotype manifested by an elongate cell body with an anterior lamella whose cell edge is divided into protrusion-forming and inactive zones. Disruption of the fibroblast microtubule cytoskeleton leads to an increase in Rho-dependent acto-myosi...

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Bibliographic Details
Main Authors: Omelchenko, T., Vasiliev, J. M., Gelfand, I. M., Feder, H. H., Bonder, E. M.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2002
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC124937/
https://ncbi.nlm.nih.gov/pubmed/12149446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.152339899
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