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Production of Active Chimeric Pediocin AcH in Escherichia coli in the Absence of Processing and Secretion Genes from the Pediococcus pap Operon

Minimum requirements have been determined for synthesis and secretion of the Pediococcus antimicrobial peptide, pediocin AcH, in Escherichia coli. The functional mature domain of pediocin AcH (Lys(+1) to Cys(+44)) is targeted into the E. coli sec machinery and secreted to the periplasm in active for...

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Autors principals: Miller, Kurt W., Schamber, Robin, Chen, Yanling, Ray, Bibek
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 1998
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC124665/
https://ncbi.nlm.nih.gov/pubmed/9435056
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