Entry of Amphotropic and 10A1 Pseudotyped Murine Retroviruses Is Restricted in Hematopoietic Stem Cell Lines

Although transduction with amphotropic murine leukemia virus (MLV) vectors has been optimized successfully for hematopoietic differentiated progenitors, gene transfer to early hematopoietic cells (stem cells) is still highly restricted. A similar restriction to gene transfer was observed in the mous...

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Bibliographic Details
Main Authors: von Laer, Dorothee, Thomsen, Silke, Vogt, Birgit, Donath, Martina, Kruppa, Joachim, Rein, Alan, Ostertag, Wolfram, Stocking, Carol
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1998
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC124622/
https://ncbi.nlm.nih.gov/pubmed/9445044
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