WIN 52035-Dependent Human Rhinovirus 16: Assembly Deficiency Caused by Mutations near the Canyon Surface

Three drug-dependent mutants of human rhinovirus 16 (HRV16) were characterized by sequence analyses of spontaneous mutant isolates and were genetically reconstructed from a parental cDNA plasmid. These mutants formed plaques in the presence but not in the absence of the selecting antiviral drug, WIN...

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Pubblicato in:	J Virol
Autori principali:	Wang, Wensheng, Lee, Wai-Ming, Mosser, Anne G., Rueckert, Roland R.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1998
Soggetti:	Animal Viruses
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC124598/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9445020/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.2.1210-1218.1998
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