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Retroviral Recombination Rates Do Not Increase Linearly with Marker Distance and Are Limited by the Size of the Recombining Subpopulation

Recombination occurs at high frequencies in all examined retroviruses. The previously determined homologous recombination rate in one retroviral replication cycle is 4% for markers 1.0 kb apart in spleen necrosis virus (SNV). This has often been used to suggest that approximately 30 to 40% of the re...

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Bibliographic Details
Main Authors: Anderson, Jeffrey A., Bowman, Ella Harvey, Hu, Wei-Shau
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1998
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC124596/
https://ncbi.nlm.nih.gov/pubmed/9445018
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