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Both the Polycythemia- and Anemia-Inducing Strains of Friend Spleen Focus-Forming Virus Induce Constitutive Activation of the Raf-1/Mitogen-Activated Protein Kinase Signal Transduction Pathway

The erythroleukemia-inducing Friend spleen focus-forming virus (SFFV) encodes a unique envelope glycoprotein which allows erythroid cells to proliferate and differentiate in the absence of erythropoietin (Epo). In an attempt to understand how the virus causes Epo independence, we have been studying...

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Autors principals: Muszynski, Karen W., Ohashi, Takashi, Hanson, Charlotte, Ruscetti, Sandra K.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 1998
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC124561/
https://ncbi.nlm.nih.gov/pubmed/9444983
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