Proteolytic Processing at the Amino Terminus of Human Coronavirus 229E Gene 1-Encoded Polyproteins: Identification of a Papain-Like Proteinase and Its Substrate

Expression of the coronavirus gene 1-encoded polyproteins, pp1a and pp1ab, is linked to a series of proteolytic events involving virus-encoded proteinases. In this study, we used transfection and immunoprecipitation assays to show that the human coronavirus 229E-encoded papain-like cysteine proteina...

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Main Authors: Herold, Jens, Gorbalenya, Alexander E., Thiel, Volker, Schelle, Barbara, Siddell, Stuart G.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 1998
Teme:
Animal Viruses
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC124560/
https://ncbi.nlm.nih.gov/pubmed/9444982
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