Reversible cardiac fibrosis and heart failure induced by conditional expression of an antisense mRNA of the mineralocorticoid receptor in cardiomyocytes

Cardiac failure is a common feature in the evolution of cardiac disease. Among the determinants of cardiac failure, the renin–angiotensin–aldosterone system has a central role, and antagonism of the mineralocorticoid receptor (MR) has been proposed as a therapeutic strategy. In this study, we questi...

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Main Authors: Beggah, Ahmed T., Escoubet, Brigitte, Puttini, Stefania, Cailmail, Stephane, Delage, Vanessa, Ouvrard-Pascaud, Antoine, Bocchi, Brigitte, Peuchmaur, Michel, Delcayre, Claude, Farman, Nicolette, Jaisser, Frederic
Formáid: Artigo
Teanga:Inglês
Foilsithe: The National Academy of Sciences 2002
Ábhair:
Biological Sciences
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC124545/
https://ncbi.nlm.nih.gov/pubmed/11997477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.102673599
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