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Paracrine in vivo inhibitory effects of hepatitis B virus X protein (HBx) on liver cell proliferation: An alternative mechanism of HBx-related pathogenesis

The role of the hepatitis B virus X protein (HBx) in the pathogenesis of hepatitis B virus (HBV) infection remains unclear. HBx exhibits pleiotropic biological effects, whose in vivo relevance is a matter for debate. In the present report, we have used a combination of HBx-expressing transgenic mice...

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Detalhes bibliográficos
Main Authors: Tralhao, J. Guilherme, Roudier, Jean, Morosan, Serban, Giannini, Carlo, Tu, Hong, Goulenok, Cyril, Carnot, Françoise, Zavala, Flora, Joulin, Virginie, Kremsdorf, Dina, Bréchot, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC124516/
https://ncbi.nlm.nih.gov/pubmed/12011457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.092657699
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