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Transmissibility of systemic amyloidosis by a prion-like mechanism

The generation of amyloid fibrils from an amyloidogenic polypeptide occurs by a nucleation-dependent process initiated in vitro by seeding the protein solution with preformed fibrils. This phenomenon is evidenced in vivo by the fact that amyloid protein A (AA) amyloidosis in mice is markedly acceler...

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Hlavní autoři: Lundmark, Katarzyna, Westermark, Gunilla T., Nyström, Sofia, Murphy, Charles L., Solomon, Alan, Westermark, Per
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences 2002
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC124514/
https://ncbi.nlm.nih.gov/pubmed/12011456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.092205999
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