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Transmissibility of systemic amyloidosis by a prion-like mechanism
The generation of amyloid fibrils from an amyloidogenic polypeptide occurs by a nucleation-dependent process initiated in vitro by seeding the protein solution with preformed fibrils. This phenomenon is evidenced in vivo by the fact that amyloid protein A (AA) amyloidosis in mice is markedly acceler...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The National Academy of Sciences
2002
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC124514/ https://ncbi.nlm.nih.gov/pubmed/12011456 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.092205999 |
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